Daniel S. McGehee

Biosciences Graduate Program Association
  1. Wolfman SL, Gill DF, Bogdanic F, Long K, Al-Hasani R, McCall JG, Bruchas MR, McGehee DS. Nicotine aversion is mediated by GABAergic interpeduncular nucleus inputs to laterodorsal tegmentum. Nat Commun. 2018 07 13; 9(1):2710. View in: PubMed

  2. Umana IC, Daniele CA, Miller BA, Abburi C, Gallagher K, Brown MA, Mason P, McGehee DS. Nicotinic modulation of descending pain control circuitry. Pain. 2017 Oct; 158(10):1938-1950. View in: PubMed

  3. Wang Q, Li D, Bubula N, Campioni MR, McGehee DS, Vezina P. Sensitizing exposure to amphetamine increases AMPA receptor phosphorylation without increasing cell surface expression in the rat nucleus accumbens. Neuropharmacology. 2017 05 01; 117:328-337. View in: PubMed

  4. Abburi C, Wolfman SL, Metz RA, Kamber R, McGehee DS, McDaid J. Tolerance to Ethanol or Nicotine Results in Increased Ethanol Self-Administration and Long-Term Depression in the Dorsolateral Striatum. eNeuro. 2016 Jul-Aug; 3(4). View in: PubMed

  5. McDaid J, Abburi C, Wolfman SL, Gallagher K, McGehee DS. Ethanol-Induced Motor Impairment Mediated by Inhibition of a7 Nicotinic Receptors. J Neurosci. 2016 07 20; 36(29):7768-78. View in: PubMed

  6. Koranda JL, Krok AC, Xu J, Contractor A, McGehee DS, Beeler JA, Zhuang X. Chronic Nicotine Mitigates Aberrant Inhibitory Motor Learning Induced by Motor Experience under Dopamine Deficiency. J Neurosci. 2016 05 11; 36(19):5228-40. View in: PubMed

  7. Lim SAO, Xia R, Ding Y, Won L, Ray WJ, Hitchcock SA, McGehee DS, Kang UJ. Enhanced histamine H2 excitation of striatal cholinergic interneurons in L-DOPA-induced dyskinesia. Neurobiol Dis. 2015 Apr; 76:67-76. View in: PubMed

  8. Lim SA, Kang UJ, McGehee DS. Striatal cholinergic interneuron regulation and circuit effects. Front Synaptic Neurosci. 2014; 6:22. View in: PubMed

  9. Augustin SM, Beeler JA, McGehee DS, Zhuang X. Cyclic AMP and afferent activity govern bidirectional synaptic plasticity in striatopallidal neurons. J Neurosci. 2014 May 07; 34(19):6692-9. View in: PubMed

  10. Koranda JL, Cone JJ, McGehee DS, Roitman MF, Beeler JA, Zhuang X. Nicotinic receptors regulate the dynamic range of dopamine release in vivo. J Neurophysiol. 2014 Jan; 111(1):103-11. View in: PubMed

  11. Umana IC, Daniele CA, McGehee DS. Neuronal nicotinic receptors as analgesic targets: it's a winding road. Biochem Pharmacol. 2013 Oct 15; 86(8):1208-14. View in: PubMed

  12. Baker LK, Mao D, Chi H, Govind AP, Vallejo YF, Iacoviello M, Herrera S, Cortright JJ, Green WN, McGehee DS, Vezina P. Intermittent nicotine exposure upregulates nAChRs in VTA dopamine neurons and sensitises locomotor responding to the drug. Eur J Neurosci. 2013 Mar; 37(6):1004-11. View in: PubMed

  13. Beeler JA, Frank MJ, McDaid J, Alexander E, Turkson S, Bernardez Sarria MS, Bernandez MS, McGehee DS, Zhuang X. A role for dopamine-mediated learning in the pathophysiology and treatment of Parkinson's disease. Cell Rep. 2012 Dec 27; 2(6):1747-61. View in: PubMed

  14. McCutcheon JE, Conrad KL, Carr SB, Ford KA, McGehee DS, Marinelli M. Dopamine neurons in the ventral tegmental area fire faster in adolescent rats than in adults. J Neurophysiol. 2012 Sep; 108(6):1620-30. View in: PubMed

  15. Leggett C, McGehee DS, Mastrianni J, Yang W, Bai T, Brorson JR. Tunicamycin produces TDP-43 cytoplasmic inclusions in cultured brain organotypic slices. J Neurol Sci. 2012 Jun 15; 317(1-2):66-73. View in: PubMed

  16. Chang B, Daniele CA, Gallagher K, Madonia M, Mitchum RD, Barrett L, Vezina P, McGehee DS. Nicotinic excitation of serotonergic projections from dorsal raphe to the nucleus accumbens. J Neurophysiol. 2011 Aug; 106(2):801-8. View in: PubMed

  17. Mao D, Gallagher K, McGehee DS. Nicotine potentiation of excitatory inputs to ventral tegmental area dopamine neurons. J Neurosci. 2011 May 04; 31(18):6710-20. View in: PubMed

  18. Ding Y, Won L, Britt JP, Lim SA, McGehee DS, Kang UJ. Enhanced striatal cholinergic neuronal activity mediates L-DOPA-induced dyskinesia in parkinsonian mice. Proc Natl Acad Sci U S A. 2011 Jan 11; 108(2):840-5. View in: PubMed

  19. McGehee DS, Oxford GS. Bradykinin modulates the electrophysiology of cultured rat sensory neurons through a pertussis toxin-insensitive G protein. Mol Cell Neurosci. 1991 Feb; 2(1):21-30. View in: PubMed

  20. Kheirbek MA, Britt JP, Beeler JA, Ishikawa Y, McGehee DS, Zhuang X. Adenylyl cyclase type 5 contributes to corticostriatal plasticity and striatum-dependent learning. J Neurosci. 2009 Sep 30; 29(39):12115-24. View in: PubMed

  21. McGehee DS. Nicotine's Allure. Neuron. 2009 Sep 10; 63(5):564-5. View in: PubMed

  22. Mao D, McGehee DS. Nicotine and behavioral sensitization. J Mol Neurosci. 2010 Jan; 40(1-2):154-63. View in: PubMed

  23. Campioni MR, Xu M, McGehee DS. Stress-induced changes in nucleus accumbens glutamate synaptic plasticity. J Neurophysiol. 2009 Jun; 101(6):3192-8. View in: PubMed

  24. Britt JP, McGehee DS. Presynaptic opioid and nicotinic receptor modulation of dopamine overflow in the nucleus accumbens. J Neurosci. 2008 Feb 13; 28(7):1672-81. View in: PubMed

  25. Lucioni A, Bales GT, Lotan TL, McGehee DS, Cook SP, Rapp DE. Botulinum toxin type A inhibits sensory neuropeptide release in rat bladder models of acute injury and chronic inflammation. BJU Int. 2008 Feb; 101(3):366-70. View in: PubMed

  26. Keath JR, Iacoviello MP, Barrett LE, Mansvelder HD, McGehee DS. Differential modulation by nicotine of substantia nigra versus ventral tegmental area dopamine neurons. J Neurophysiol. 2007 Dec; 98(6):3388-96. View in: PubMed

  27. Vezina P, McGehee DS, Green WN. Exposure to nicotine and sensitization of nicotine-induced behaviors. Prog Neuropsychopharmacol Biol Psychiatry. 2007 Nov 15; 31(8):1625-38. View in: PubMed

  28. Mansvelder HD, Fagen ZM, Chang B, Mitchum R, McGehee DS. Bupropion inhibits the cellular effects of nicotine in the ventral tegmental area. Biochem Pharmacol. 2007 Oct 15; 74(8):1283-91. View in: PubMed

  29. Fagen ZM, Mitchum R, Vezina P, McGehee DS. Enhanced nicotinic receptor function and drug abuse vulnerability. J Neurosci. 2007 Aug 15; 27(33):8771-8. View in: PubMed

  30. McGehee DS. Nicotine and synaptic plasticity in prefrontal cortex. Sci STKE. 2007 Aug 14; 2007(399):pe44. View in: PubMed

  31. McGehee DS. GIRK channels as a target for SSRIs. Focus on "reduced 5-HT1A- and GABAB receptor function in dorsal raphe neurons upon chronic fluoxetine treatment of socially stressed rats". J Neurophysiol. 2007 Jul; 98(1):1-2. View in: PubMed

  32. Young KC, McGehee DS, Brorson JR. Glutamate receptor expression and chronic glutamate toxicity in rat motor cortex. Neurobiol Dis. 2007 Apr; 26(1):78-85. View in: PubMed

  33. McGehee DS. Nicotinic and opioid receptor interactions in nicotine addiction. Mol Interv. 2006 Dec; 6(6):311-4. View in: PubMed

  34. Cagniard B, Beeler JA, Britt JP, McGehee DS, Marinelli M, Zhuang X. Dopamine scales performance in the absence of new learning. Neuron. 2006 Sep 07; 51(5):541-7. View in: PubMed

  35. Genzen JR, McGehee DS. Nicotinic modulation of GABAergic synaptic transmission in the spinal cord dorsal horn. Brain Res. 2005 Jan 21; 1031(2):229-37. View in: PubMed

  36. Suzuki T, Abe Y, McGehee DS, Keath JR, Yajima H, Sharma K, Brorson JR. Long-lived retrograde fluorescent labeling of corticospinal neurons in the living animal. Brain Res Brain Res Protoc. 2004 Aug; 13(3):183-8. View in: PubMed

  37. Fagen ZM, Mansvelder HD, Keath JR, McGehee DS. Short- and long-term modulation of synaptic inputs to brain reward areas by nicotine. Ann N Y Acad Sci. 2003 Nov; 1003:185-95. View in: PubMed

  38. Mansvelder HD, De Rover M, McGehee DS, Brussaard AB. Cholinergic modulation of dopaminergic reward areas: upstream and downstream targets of nicotine addiction. Eur J Pharmacol. 2003 Nov 07; 480(1-3):117-23. View in: PubMed

  39. Genzen JR, McGehee DS. Short- and long-term enhancement of excitatory transmission in the spinal cord dorsal horn by nicotinic acetylcholine receptors. Proc Natl Acad Sci U S A. 2003 May 27; 100(11):6807-12. View in: PubMed

  40. Mansvelder HD, McGehee DS. Cellular and synaptic mechanisms of nicotine addiction. J Neurobiol. 2002 Dec; 53(4):606-17. View in: PubMed

  41. McGehee DS. Nicotinic receptors and hippocampal synaptic plasticity ... it's all in the timing. Trends Neurosci. 2002 Apr; 25(4):171-2. View in: PubMed

  42. Mansvelder HD, Keath JR, McGehee DS. Synaptic mechanisms underlie nicotine-induced excitability of brain reward areas. Neuron. 2002 Mar 14; 33(6):905-19. View in: PubMed

  43. Genzen JR, Van Cleve W, McGehee DS. Dorsal root ganglion neurons express multiple nicotinic acetylcholine receptor subtypes. J Neurophysiol. 2001 Oct; 86(4):1773-82. View in: PubMed

  44. Kung AY, Rick C, O'Shea S, Harrison NL, McGehee DS. Expression of glycine receptors in rat sensory neurons vs. HEK293 cells yields different functional properties. Neurosci Lett. 2001 Aug 31; 309(3):202-6. View in: PubMed

  45. Girod R, Barazangi N, McGehee D, Role LW. Facilitation of glutamatergic neurotransmission by presynaptic nicotinic acetylcholine receptors. Neuropharmacology. 2000 Oct; 39(13):2715-25. View in: PubMed

  46. Mansvelder HD, McGehee DS. Long-term potentiation of excitatory inputs to brain reward areas by nicotine. Neuron. 2000 Aug; 27(2):349-57. View in: PubMed

  47. McGehee DS, Krasowski MD, Fung DL, Wilson B, Gronert GA, Moss J. Cholinesterase inhibition by potato glycoalkaloids slows mivacurium metabolism. Anesthesiology. 2000 Aug; 93(2):510-9. View in: PubMed

  48. Devay P, McGehee DS, Yu CR, Role LW. Target-specific control of nicotinic receptor expression at developing interneuronal synapses in chick. Nat Neurosci. 1999 Jun; 2(6):528-34. View in: PubMed

  49. Girod R, Crabtree G, Ernstrom G, Ramirez-Latorre J, McGehee D, Turner J, Role L. Heteromeric complexes of alpha 5 and/or alpha 7 subunits. Effects of calcium and potential role in nicotine-induced presynaptic facilitation. Ann N Y Acad Sci. 1999 Apr 30; 868:578-90. View in: PubMed

  50. McGehee DS. Molecular diversity of neuronal nicotinic acetylcholine receptors. Ann N Y Acad Sci. 1999 Apr 30; 868:565-77. View in: PubMed

  51. Rakhilin S, Drisdel RC, Sagher D, McGehee DS, Vallejo Y, Green WN. alpha-bungarotoxin receptors contain alpha7 subunits in two different disulfide-bonded conformations. J Cell Biol. 1999 Jul 12; 146(1):203-18. View in: PubMed

  52. McGehee DS, Aldersberg M, Liu KP, Hsuing S, Heath MJ, Tamir H. Mechanism of extracellular Ca2+ receptor-stimulated hormone release from sheep thyroid parafollicular cells. J Physiol. 1997 Jul 01; 502 ( Pt 1):31-44. View in: PubMed

  53. Krasowski MD, McGehee DS, Moss J. Natural inhibitors of cholinesterases: implications for adverse drug reactions. Can J Anaesth. 1997 May; 44(5 Pt 1):525-34. View in: PubMed

  54. McGehee DS, Role LW. Neurobiology: memories of nicotine. Nature. 1996 Oct 24; 383(6602):670-1. View in: PubMed

  55. McGehee DS, Role LW. Presynaptic ionotropic receptors. Curr Opin Neurobiol. 1996 Jun; 6(3):342-9. View in: PubMed

  56. McGehee DS, Role LW. Physiological diversity of nicotinic acetylcholine receptors expressed by vertebrate neurons. Annu Rev Physiol. 1995; 57:521-46. View in: PubMed

  57. McGehee DS, Heath MJ, Gelber S, Devay P, Role LW. Nicotine enhancement of fast excitatory synaptic transmission in CNS by presynaptic receptors. Science. 1995 Sep 22; 269(5231):1692-6. View in: PubMed

  58. Seroogy KB, Mohapatra NK, Lund PK, RĂ©thelyi M, McGehee DS, Perl ER. Species-specific expression of cholecystokinin messenger RNA in rodent dorsal root ganglia. Brain Res Mol Brain Res. 1990 Feb; 7(2):171-6. View in: PubMed

  59. Naruse K, McGehee DS, Oxford GS. Differential responses of Ca-activated K channels to bradykinin in sensory neurons and F-11 cells. Am J Physiol. 1992 Feb; 262(2 Pt 1):C453-60. View in: PubMed

  60. McGehee DS, Goy MF, Oxford GS. Involvement of the nitric oxide-cyclic GMP pathway in the desensitization of bradykinin responses of cultured rat sensory neurons. Neuron. 1992 Aug; 9(2):315-24. View in: PubMed